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Dynamics of initiation, termination and reinitiation of DNA translocation by the motor protein EcoR124I

Our function was swiftly followed up by Other individuals, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 printed their results on transistors created from solitary- and multi-walled carbon nanotubes in Applied Physics Letters.

2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and initial at any time research of your dynamics DNA supercoils and the discovery of supercoil hopping

During the decades pursuing these discoveries, my exploration passions shifted to biophysics and nanobiology, and I turned fewer involved with the development of nanotube electronics. The focus of numerous scientists in the field also shifted to graphene (exactly where, funnily sufficient, the 1st graphene ribbons ended up referred to as ‘nanotubes which are Slash open up along their duration’) immediately after the discovery of the two-dimensional substance in 2004.

Duration Charge of specific carbon nanotubes by nanostructuring Together with the scanning tunneling microscope

Example (1) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is shown in grey, the rim of your pore is highlighted in pink, plus a 3D rendering with the motion from the DNA rod is displayed.

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1). The existing–voltage curves showed important modulations with gate voltage, even at room temperature, which was in keeping with band bending inside a ~0.six eV bandgap semiconducting nanotube. These information also confirmed which the conductance may be modulated by six orders of magnitude by shifting the gate voltage. The results of this do the job — a space-temperature transistor comprised of just one carbon nanotube molecule — ended up published in Character in May perhaps 1998.

Considering that 2000 he moved to single-molecule biophysics and nanobiology, with investigate from reports of DNA loop extrusion and supercoiling to DNA translocation via nanopores. Extra just lately his study has centered on learning chromatin composition and cell division with microbes on chip, although he is also aiming to ultimately Create artificial cells from the bottom up.

Nanoscientist Cees Dekker is really an amiable and flamboyant gentleman who appears A lot young when compared to the sixty two a long time he really is – fashionable Eyeglasses, psychedelic shirt, participating smile – but not one to squander time. He normally takes his time, but no more than necessary.

2008, first observation of protein-coated DNA translocation through nanopores; resolved the origin of the electrophoretic drive on DNA in nanopores; found out an important velocity increase of microtubules in electric fields; found out an anomalous electro-hydrodynamic orientation of microtubules; and solved the origin of sound in carbon nanotubes in liquid

2004, discovery of new physics in translocation of DNA by nanopores; very first experimental study of ions conduction in nanofluidic channels; to start ceesdekker with electrochemistry with specific single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; very first electrical docking of microtubules on kinesin-coated nanostructures; first biophysics characterization with the mechanical Qualities of double-stranded RNA; and to start with solitary-molecule analyze of DNA translocation by a restriction-modification enzyme.